A single injection of Dysport (abobotulinumtoxinA) significantly helped children with cerebral palsy to achieve pre-defined functional goals in difficulties such as walking and endurance, according to a study published in the Journal of Child Neurology.The study, “AbobotulinumtoxinA (Dysport®) boost Function According to Goal Attainment in Children With Dynamic Equinus Due to Cerebral Palsy,”
All of the children, ages 2 to 17, entered the study able to walk, but had a characteristic walking pattern of tiptoeing when taking a step.The children were separated into three groups. Those in the first two received injections of Dysport in each leg at one of two different doses (10 or 15 units per kilogram, respectively) plus their current standard of care. Those in the third group were injected with an inactive drug (placebo) alongside their current standard of care. (Dysport is an FDA-approved treatment for limb spasticity in children and adults.)Functional goals were measured using the Goal Attainment Scaling (GAS), a method that relies on a written guide of wanted goals developed between the clinicians and, in this case, the children’s parent or guardian.